Mistletoe, as we all know, is a parasitic plant that draws the host tree’s carbohydrates into itself as this activity can reduce the health of the particular branch to which the mistletoe is attached and minimize fruit yield. The little shrub-like plant sends out root type organs, called haustoria, into the cambium of the tree and pirates the tree’s carbohydrate and moisture sources. It is easy to kill mistletoe growth, but the roots can be persistent and the plant may simply spring back. Simply cutting back the twigs and leaves will not kill mistletoe and you need to actively kill the roots and, therefore, the entire plant.

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Source: Gardening Know How